PhD Fellowship in Epigenetics and Signal Transduction in Cancer, BRIC, University of Copenhagen, Denmark

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The research group of Associate Prof. Morten Frödin has an open PhD fellowship. Our group is part of BRIC and Centre for Epigenetics, University of Copenhagen. Our research focuses on cellular regulation and signal transduction via protein kinase cascades downstream of RAS and PI3 kinase proto-oncogenes.

Research area of the present position
The exploding field of Epigenetics aims to uncover how protein complexes regulate chromatin structure to control gene expression. Within this field, we conduct projects focusing to understand how extracellular signals acting via RAS-activated protein kinase cascades exert epigenetic control of gene expression in epithelial cells and how this contributes to induction of an invasive, metastatic gene program and phenotype in carcinoma cells. We exploit cutting-edge techniques like genome-wide RNA interference screening, Solexa/Illumina RNA/DNA deep-sequencing and revolutionary new Zinc Finger Nuclease (ZFN)-based genomic engineering technologies to genetically modify cell lines and mice. The project is very collaborative, involving interactions with other scientists in our group, at BRIC and abroad.

About BRIC
We offer a creative and stimulating scientific atmosphere at BRIC, which is an elite research centre with excellent facilities and a dynamic, young and international research environment close to the heart of Copenhagen. As a PhD fellow, you will be enrolled in BRIC’s PhD School, MoMeD, which organizes seminars, courses and summer school. Read more about Frödin Group, BRIC, Centre for Epigenetics and MoMeD on www.bric.ku.dk


Qualifications
We are seeking a highly motivated, ambitious and good-spirited colleague with a Master Degree in Biochemistry, Molecular Biology or equivalent. It is a condition that the MSc is assessed equivalent to a Danish MSc by the Danish Agency for International Education.

Employment and salary
The employment and place of work is BRIC, University of Copenhagen. The position is for 3 years, ideally starting May/June 2010. The PhD study must be completed in accordance with the ministerial orders from the Ministry of Education on the PhD degree and the University’s rules on achieving the degree. The student will be enrolled at Faculty of Health Sciences and be part of BRIC’s research school MoMeD.

Salary, pension and terms of employment are in accordance with the agreement between the Ministry of Finance and The Danish Confederation of Professional Associations on Academics in the State. Depending on seniority, the monthly salary begins around 25.000 DDK (ca. 3.350 Euro) plus pension.

Application
The application must be submitted in 3 printed copies and consist of the following:

  1. Motivated letter of application
  2. “Cover sheet” (PhD), which can be downloaded on www.bric.ku.dk/jobs
  3. Curriculum vitae
  4. Publication list
  5. Copy of degree certificate(s)

The application should be marked “PhD Frödin” and send it to: BRIC, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark.

Furthermore, the applicant should provide two letters of recommendation; sent directly to recommend[at]bric.ku.dk from the supporting persons.

Deadline: May 20, 2010 at 12.00 pm.

NB: Only printed applications received by ordinary post, in time and consisting of the above listed documents will be considered.

BRIC and University of Copenhagen wish to reflect the diversity of society and welcome applications from all qualified candidates regardless of personal background.


Disclaimer: Every effort has been made to ensure the above information is current and correct. However, applicants should contact the appropriate administering body before making an application, as details do change frequently.

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